New discovery of resveratrol in the treatment of diabetes

After Jason Dyck of the University of Alberta found that resveratrol has the potential to treat diabetes, researchers from Sakura medical center of Tohoku University in Japan found a new role of resveratrol in the treatment of diabetes through clinical research: it can reduce the oxidative pressure of type II diabetes patients and alleviate arteriosclerosis.

Placebo controlled double-blind clinical study

The researchers recruited 50 patients with type II diabetes and randomly divided them into two groups: one group received resveratrol oral supplement and the other group received placebo for 12 weeks. The results showed that in the resveratrol group, the arteriosclerosis index and oxidative stress were significantly decreased, and the body weight and BMI index were also slightly decreased. At the same time, the new systolic blood pressure also decreased significantly.

Mechanism of action

The reduction of oxidative stress and weight loss may be related to the mechanism of atherosclerosis remission. Arteriosclerosis shows reversible vascular dysfunction, is a good marker of vascular injury, and has good benefits for evaluating the effect of resveratrol. In addition, the reduction of oxidative stress after the use of resveratrol supplementation is also considered to help improve the symptoms of diabetes. Potential mechanisms also include: resveratrol can improve endothelial function.

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This study found that resveratrol supplementation can improve the oxidative stress and arterial function of patients with type II diabetes. However, it is still a small and short-term study after all. It is not known what effect resveratrol supplementation will have if it is used for a long time. Therefore, we expect that there will be more large-scale and long-term clinical studies in the future to confirm the specific role of resveratrol in the treatment of diabetes.